![]() ![]() However, the maximal individual cv observed was 78.4%. Median coefficients of variation (cv) for the individual subject ranged from 9.7% (interpulse interval and endogenous half-life) to 37.7% (mass per burst). However, most parameters showed low correlation coefficients between the three study periods, suggesting that substantial individual variations might contribute to the more reliable group results. As a group, no significant differences between the three profile series were found for any of the calculated parameters of LH concentration or LH secretion. In addition, a simultaneous multiple parameter DECONVOLUTION was applied. ![]() Conventional pulse detection was carried out with PULSAR and CLUSTER programs. Blood samples were taken at 10-min intervals and plasma luteinizing hormone (LH) was determined in the same immunoradiometric assay using monoclonal antibodies. The ages of the volunteers ranged from 19 to 25 years, and heights and weights were within normal limits. ISSN 0804–4643Ĭharacteristics of spontaneous pulsatile luteinizing hormone secretion were compared in ten young healthy men in three 24-h profiles obtained at intervals of 14 days and 3 months. Variability of pulsatile luteinizing hormone secretion in young male volunteers. ![]() Partsch C-J, Abrahams S, Herholz N, Peter M, Veldhuis JD, Sippell WG.
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